Site CDNA-Pos Description Allele1 AD-freq ND-freq RD-freq Total-freq Allele2 AD-freq ND-freq RD-freq Total-freq Protein-Pos Codon1 Codon2 Amino1 Amino2 000220 00000 ------------ T 0.74 0.62 0.67 0.68 C 0.26 0.38 0.33 0.32 0000 --- --- --- --- 000240 00000 ------------ T 0.76 0.62 0.72 0.70 C 0.24 0.38 0.28 0.30 0000 --- --- --- --- 000266 00000 ------------ A 0.91 1.00 1.00 0.97 G 0.09 0.00 0.00 0.03 0000 --- --- --- --- 000557 00000 ------------ C 0.80 0.83 0.71 0.78 T 0.20 0.17 0.29 0.22 0000 --- --- --- --- 000848 00000 ------------ T 0.91 0.90 0.88 0.89 C 0.09 0.10 0.12 0.11 0000 --- --- --- --- 000870 00000 ------------ C 0.93 1.00 1.00 0.98 G 0.07 0.00 0.00 0.02 0000 --- --- --- --- 000923 00000 ------------ G 0.52 0.58 0.56 0.56 A 0.48 0.42 0.44 0.44 0000 --- --- --- --- 001019 00000 ------------ C 1.00 0.90 0.86 0.91 T 0.00 0.10 0.14 0.09 0000 --- --- --- --- 001153 00000 ------------ G 0.93 1.00 1.00 0.98 A 0.07 0.00 0.00 0.02 0000 --- --- --- --- 001263 00000 ------------ C 1.00 0.98 0.98 0.99 A 0.00 0.02 0.02 0.01 0000 --- --- --- --- 001265 00000 ------------ C 0.43 0.63 0.54 0.54 A 0.57 0.37 0.46 0.46 0000 --- --- --- --- 001856 00066 5' UTR G 0.96 1.00 1.00 0.99 A 0.04 0.00 0.00 0.01 0000 --- --- --- --- 001986 00196 SYNON C 0.90 1.00 1.00 0.97 A 0.10 0.00 0.00 0.03 0022 ACC ACA THR(T) THR(T) 002133 00000 ------------ C 0.88 0.89 1.00 0.92 A 0.12 0.11 0.00 0.08 0000 --- --- --- --- 002187 00000 ------------ T 0.41 0.61 0.57 0.53 C 0.59 0.39 0.43 0.47 0000 --- --- --- --- 002240 00000 ------------ G 0.76 0.76 0.61 0.71 A 0.24 0.24 0.39 0.29 0000 --- --- --- --- 002317 00000 ------------ G 0.76 0.73 0.59 0.69 A 0.24 0.27 0.41 0.31 0000 --- --- --- --- 002618 00000 ------------ G 0.98 1.00 1.00 0.99 A 0.02 0.00 0.00 0.01 0000 --- --- --- --- 003101 00000 ------------ A 0.96 1.00 1.00 0.98 G 0.04 0.00 0.00 0.02 0000 --- --- --- --- 003379 00000 ------------ + 0.52 0.24 0.16 0.31 - 0.48 0.76 0.84 0.69 0000 --- --- --- --- 003399 00000 ------------ T 0.76 0.63 0.70 0.70 A 0.24 0.37 0.30 0.30 0000 --- --- --- --- 003581 00000 ------------ T 0.79 0.65 0.73 0.72 C 0.21 0.35 0.27 0.28 0000 --- --- --- --- 003686 00000 ------------ G 0.88 0.85 0.96 0.90 C 0.12 0.15 0.04 0.10 0000 --- --- --- --- 004791 00000 ------------ T 0.96 0.94 1.00 0.96 G 0.04 0.06 0.00 0.04 0000 --- --- --- --- 004943 00000 ------------ T 1.00 0.98 1.00 0.99 G 0.00 0.02 0.00 0.01 0000 --- --- --- --- 004948 00000 ------------ A 0.91 0.81 0.56 0.76 G 0.09 0.19 0.44 0.24 0000 --- --- --- --- 004957 00000 ------------ G 0.98 1.00 1.00 0.99 A 0.02 0.00 0.00 0.01 0000 --- --- --- --- 005808 00000 ------------ C 0.95 1.00 1.00 0.99 T 0.05 0.00 0.00 0.01 0000 --- --- --- --- 005810 00000 ------------ + 0.81 0.81 0.87 0.83 - 0.19 0.19 0.13 0.17 0000 --- --- --- --- 005979 00000 ------------ G 0.88 0.60 0.67 0.71 A 0.12 0.40 0.33 0.29 0000 --- --- --- --- 005990 00000 ------------ G 0.97 1.00 1.00 0.99 C 0.03 0.00 0.00 0.01 0000 --- --- --- --- 006175 00000 ------------ C 1.00 0.94 1.00 0.98 T 0.00 0.06 0.00 0.02 0000 --- --- --- --- 006221 00000 ------------ A 0.98 1.00 1.00 0.99 G 0.02 0.00 0.00 0.01 0000 --- --- --- --- 006239 00000 ------------ C 0.93 1.00 1.00 0.98 A 0.07 0.00 0.00 0.02 0000 --- --- --- --- 006314 00000 ------------ G 0.68 0.67 0.40 0.58 A 0.32 0.33 0.60 0.42 0000 --- --- --- --- 006427 00000 ------------ G 0.98 1.00 1.00 0.99 A 0.02 0.00 0.00 0.01 0000 --- --- --- --- 006914 00000 ------------ G 0.80 0.91 0.83 0.85 A 0.20 0.09 0.17 0.15 0000 --- --- --- --- 007131 00000 ------------ T 0.98 1.00 1.00 0.99 C 0.02 0.00 0.00 0.01 0000 --- --- --- --- 007244 00000 ------------ C 0.88 0.81 0.57 0.75 T 0.12 0.19 0.43 0.25 0000 --- --- --- --- 007278 00000 ------------ T 0.93 1.00 1.00 0.98 C 0.07 0.00 0.00 0.02 0000 --- --- --- --- 007283 00000 ------------ + 0.23 0.13 0.17 0.17 - 0.78 0.87 0.83 0.83 0000 --- --- --- --- 007289 00000 ------------ C 0.82 0.83 0.93 0.86 A 0.17 0.17 0.07 0.14 0000 --- --- --- --- 007616 00000 ------------ C 0.88 0.88 0.75 0.84 A 0.12 0.12 0.25 0.16 0000 --- --- --- --- 008184 00000 ------------ T 0.75 0.85 0.97 0.86 C 0.25 0.15 0.03 0.14 0000 --- --- --- --- 008274 00000 ------------ C 0.67 0.83 0.93 0.80 T 0.33 0.17 0.07 0.20 0000 --- --- --- --- 008331 00000 ------------ A 0.98 1.00 1.00 0.99 G 0.02 0.00 0.00 0.01 0000 --- --- --- --- 008436 00000 ------------ C 0.88 0.61 0.69 0.72 A 0.12 0.39 0.31 0.28 0000 --- --- --- --- 008695 00000 ------------ G 0.36 0.57 0.70 0.56 C 0.64 0.43 0.30 0.44 0000 --- --- --- --- 008742 00000 ------------ A 0.93 1.00 1.00 0.98 G 0.07 0.00 0.00 0.02 0000 --- --- --- --- 008764 00000 ------------ G 0.90 1.00 0.91 0.94 T 0.10 0.00 0.09 0.06 0000 --- --- --- --- 008985 00000 ------------ G 0.98 1.00 1.00 0.99 A 0.02 0.00 0.00 0.01 0000 --- --- --- --- 009057 00000 ------------ G 1.00 0.94 1.00 0.98 T 0.00 0.06 0.00 0.02 0000 --- --- --- --- 009178 00000 ------------ T 0.98 0.94 0.92 0.94 C 0.02 0.06 0.08 0.06 0000 --- --- --- --- 009493 00000 ------------ T 0.98 1.00 1.00 0.99 C 0.02 0.00 0.00 0.01 0000 --- --- --- --- 009755 00000 ------------ T 0.88 1.00 1.00 0.96 G 0.12 0.00 0.00 0.04 0000 --- --- --- --- 010491 00000 ------------ G 0.91 1.00 1.00 0.97 A 0.09 0.00 0.00 0.03 0000 --- --- --- --- 010694 00000 ------------ C 0.91 1.00 1.00 0.97 T 0.09 0.00 0.00 0.03 0000 --- --- --- --- 010779 00000 ------------ A 0.91 1.00 1.00 0.97 G 0.09 0.00 0.00 0.03 0000 --- --- --- --- 010921 00000 ------------ G 0.89 0.81 0.58 0.76 A 0.11 0.19 0.42 0.24 0000 --- --- --- --- 010924 00000 ------------ C 1.00 0.98 1.00 0.99 T 0.00 0.02 0.00 0.01 0000 --- --- --- --- 010934 00000 ------------ A 0.98 1.00 1.00 0.99 G 0.02 0.00 0.00 0.01 0000 --- --- --- --- 011332 00000 ------------ C 0.89 0.81 0.58 0.76 T 0.11 0.19 0.42 0.24 0000 --- --- --- --- 011456 00000 ------------ T 0.93 1.00 1.00 0.98 C 0.07 0.00 0.00 0.02 0000 --- --- --- --- 011510 00000 ------------ C 0.87 0.81 0.58 0.75 A 0.13 0.19 0.42 0.25 0000 --- --- --- --- 011581 00000 ------------ C 0.98 0.98 0.85 0.94 T 0.02 0.02 0.15 0.06 0000 --- --- --- --- 011651 00000 ------------ T 0.85 0.94 1.00 0.93 C 0.15 0.06 0.00 0.07 0000 --- --- --- --- 011795 00000 ------------ C 0.96 1.00 1.00 0.99 G 0.04 0.00 0.00 0.01 0000 --- --- --- --- 011913 00000 ------------ C 0.85 1.00 1.00 0.95 T 0.15 0.00 0.00 0.05 0000 --- --- --- --- 012103 00000 ------------ G 0.98 0.98 0.96 0.97 A 0.02 0.02 0.04 0.03 0000 --- --- --- --- 013384 00991 SYNON C 1.00 0.92 0.90 0.94 T 0.00 0.08 0.10 0.06 0287 TTC TTT PHE(F) PHE(F) 013477 00000 ------------ T 0.57 0.90 0.88 0.78 G 0.43 0.10 0.12 0.22 0000 --- --- --- --- 013482 00000 ------------ A 0.46 0.90 0.88 0.75 G 0.54 0.10 0.12 0.25 0000 --- --- --- --- 013543 00000 ------------ G 1.00 0.98 1.00 0.99 A 0.00 0.02 0.00 0.01 0000 --- --- --- --- 013641 00000 ------------ A 0.50 0.57 0.62 0.56 G 0.50 0.43 0.38 0.44 0000 --- --- --- --- 013683 00000 ------------ A 1.00 1.00 0.96 0.99 G 0.00 0.00 0.04 0.01 0000 --- --- --- --- 013717 00000 ------------ C 0.96 1.00 1.00 0.99 T 0.04 0.00 0.00 0.01 0000 --- --- --- --- 013749 00000 ------------ C 1.00 1.00 0.96 0.99 T 0.00 0.00 0.04 0.01 0000 --- --- --- --- 013765 00000 ------------ A 0.72 0.44 0.37 0.51 C 0.28 0.56 0.63 0.49 0000 --- --- --- --- 014079 00000 ------------ G 0.72 0.44 0.44 0.53 A 0.28 0.56 0.56 0.47 0000 --- --- --- --- 014192 00000 ------------ G 0.91 1.00 1.00 0.97 A 0.09 0.00 0.00 0.03 0000 --- --- --- --- 014210 00000 ------------ C 0.98 1.00 1.00 0.99 T 0.02 0.00 0.00 0.01 0000 --- --- --- --- 014258 00000 ------------ A 0.41 0.79 0.83 0.68 G 0.59 0.21 0.17 0.32 0000 --- --- --- --- 014318 00000 ------------ G 0.59 0.79 0.83 0.74 A 0.41 0.21 0.17 0.26 0000 --- --- --- --- 014539 00000 ------------ T 0.81 0.83 0.88 0.84 A 0.19 0.17 0.12 0.16 0000 --- --- --- --- 015231 00000 ------------ C 0.94 1.00 1.00 0.98 T 0.06 0.00 0.00 0.02 0000 --- --- --- --- 015407 00000 ------------ A 0.50 0.67 0.64 0.61 T 0.50 0.33 0.36 0.39 0000 --- --- --- --- 015419 00000 ------------ G 0.88 0.57 0.61 0.67 A 0.12 0.43 0.39 0.33 0000 --- --- --- --- 015542 00000 ------------ C 0.89 1.00 1.00 0.96 T 0.11 0.00 0.00 0.04 0000 --- --- --- --- 015639 00000 ------------ A 0.85 1.00 1.00 0.95 G 0.15 0.00 0.00 0.05 0000 --- --- --- --- 015689 00000 ------------ + 0.47 0.32 0.36 0.39 - 0.53 0.68 0.64 0.61 0000 --- --- --- --- 015800 00000 ------------ T 0.93 0.84 0.83 0.87 A 0.07 0.16 0.17 0.13 0000 --- --- --- --- 015830 00000 ------------ C 0.79 0.98 1.00 0.92 A 0.21 0.02 0.00 0.08 0000 --- --- --- --- 015913 00000 ------------ C 0.83 1.00 1.00 0.94 G 0.17 0.00 0.00 0.06 0000 --- --- --- --- 015963 00000 ------------ T 0.54 0.67 0.63 0.61 C 0.46 0.33 0.37 0.39 0000 --- --- --- --- 015972 00000 ------------ C 0.61 0.67 0.60 0.63 T 0.39 0.33 0.40 0.37 0000 --- --- --- --- 016016 00000 ------------ T 0.63 0.79 0.82 0.75 C 0.37 0.21 0.18 0.25 0000 --- --- --- --- 016859 00000 ------------ A 0.72 0.77 0.73 0.74 G 0.28 0.23 0.27 0.26 0000 --- --- --- --- 016863 00000 ------------ A 0.98 1.00 1.00 0.99 G 0.02 0.00 0.00 0.01 0000 --- --- --- --- 016890 00000 ------------ T 1.00 1.00 0.98 0.99 G 0.00 0.00 0.02 0.01 0000 --- --- --- --- 016935 00000 ------------ T 0.98 1.00 1.00 0.99 A 0.02 0.00 0.00 0.01 0000 --- --- --- --- 016979 00000 ------------ G 0.80 0.88 0.81 0.83 T 0.20 0.12 0.19 0.17 0000 --- --- --- --- 017025 00000 ------------ T 0.98 0.92 0.92 0.94 G 0.02 0.08 0.08 0.06 0000 --- --- --- --- 017154 00000 ------------ G 0.93 1.00 1.00 0.98 A 0.07 0.00 0.00 0.02 0000 --- --- --- --- 017216 00000 ------------ G 0.89 0.52 0.60 0.66 A 0.11 0.48 0.40 0.34 0000 --- --- --- --- 017274 00000 ------------ C 0.97 0.92 0.91 0.93 T 0.03 0.08 0.09 0.07 0000 --- --- --- --- 017328 00000 ------------ T 0.98 0.98 1.00 0.99 C 0.02 0.02 0.00 0.01 0000 --- --- --- --- 017444 00000 ------------ A 0.98 1.00 1.00 0.99 C 0.02 0.00 0.00 0.01 0000 --- --- --- --- 017483 00000 ------------ G 0.89 0.56 0.62 0.69 A 0.11 0.44 0.38 0.31 0000 --- --- --- --- 018388 00000 ------------ C 0.93 1.00 1.00 0.98 T 0.07 0.00 0.00 0.02 0000 --- --- --- --- 018413 00000 ------------ T 0.72 0.77 0.73 0.74 G 0.28 0.23 0.27 0.26 0000 --- --- --- --- 018446 00000 ------------ A 0.98 1.00 1.00 0.99 G 0.02 0.00 0.00 0.01 0000 --- --- --- --- 018580 00000 ------------ C 0.98 1.00 1.00 0.99 T 0.02 0.00 0.00 0.01 0000 --- --- --- --- 018597 00000 ------------ A 0.84 0.60 0.66 0.70 T 0.16 0.40 0.34 0.30 0000 --- --- --- --- 018733 00000 ------------ A 0.95 0.57 0.62 0.70 G 0.05 0.43 0.38 0.30 0000 --- --- --- --- 018921 00000 ------------ G 1.00 0.92 0.91 0.94 A 0.00 0.08 0.09 0.06 0000 --- --- --- --- 019050 00000 ------------ G 1.00 0.98 1.00 0.99 A 0.00 0.02 0.00 0.01 0000 --- --- --- --- 019561 00000 ------------ G 0.95 0.98 0.98 0.97 A 0.05 0.02 0.02 0.03 0000 --- --- --- --- 019606 00000 ------------ C 0.83 1.00 1.00 0.95 T 0.17 0.00 0.00 0.05 0000 --- --- --- --- 019700 00000 ------------ T 0.96 1.00 1.00 0.99 C 0.04 0.00 0.00 0.01 0000 --- --- --- --- 019881 00000 ------------ G 0.97 1.00 1.00 0.99 T 0.03 0.00 0.00 0.01 0000 --- --- --- --- 020284 00000 ------------ T 0.97 1.00 1.00 0.99 C 0.03 0.00 0.00 0.01 0000 --- --- --- --- 020354 00000 ------------ G 0.54 0.79 0.83 0.72 A 0.46 0.21 0.17 0.28 0000 --- --- --- --- 020374 00000 ------------ C 0.89 1.00 1.00 0.96 T 0.11 0.00 0.00 0.04 0000 --- --- --- --- 020442 00000 ------------ T 0.97 1.00 1.00 0.99 G 0.03 0.00 0.00 0.01 0000 --- --- --- --- 020446 00000 ------------ T 0.97 0.98 0.98 0.98 C 0.03 0.02 0.02 0.02 0000 --- --- --- --- 020457 00000 ------------ C 0.88 1.00 1.00 0.96 T 0.12 0.00 0.00 0.04 0000 --- --- --- --- 020910 00000 ------------ A 0.88 0.55 0.57 0.65 G 0.12 0.45 0.43 0.35 0000 --- --- --- --- 021126 01298 NON-SYN G 1.00 0.97 0.97 0.98 C 0.00 0.03 0.03 0.02 0390 GCC CCC ALA(A) PRO(P) 021498 00000 ------------ A 0.87 1.00 1.00 0.95 G 0.13 0.00 0.00 0.05 0000 --- --- --- --- 021579 00000 ------------ G 0.95 1.00 1.00 0.99 T 0.05 0.00 0.00 0.01 0000 --- --- --- --- 021580 00000 ------------ C 0.90 0.75 0.73 0.79 T 0.10 0.25 0.27 0.21 0000 --- --- --- --- 022127 01394 NON-SYN A 0.36 0.65 0.67 0.56 G 0.64 0.35 0.33 0.44 0422 ATC GTC ILE(I) VAL(V) 022162 01429 SYNON G 0.89 1.00 1.00 0.96 A 0.11 0.00 0.00 0.04 0433 GTG GTA VAL(V) VAL(V) 022337 00000 ------------ T 0.90 0.98 1.00 0.96 C 0.10 0.02 0.00 0.04 0000 --- --- --- --- 022349 00000 ------------ A 1.00 0.94 1.00 0.98 G 0.00 0.06 0.00 0.02 0000 --- --- --- --- 022351 00000 ------------ G 1.00 0.94 1.00 0.98 A 0.00 0.06 0.00 0.02 0000 --- --- --- --- 022352 00000 ------------ A 1.00 0.94 1.00 0.98 C 0.00 0.06 0.00 0.02 0000 --- --- --- --- 022480 00000 ------------ C 0.90 0.98 1.00 0.96 G 0.10 0.02 0.00 0.04 0000 --- --- --- --- 022554 00000 ------------ T 0.89 0.98 1.00 0.96 C 0.11 0.02 0.00 0.04 0000 --- --- --- --- 022562 00000 ------------ T 0.89 1.00 1.00 0.97 G 0.11 0.00 0.00 0.03 0000 --- --- --- --- 022683 00000 ------------ G 0.89 0.98 1.00 0.96 A 0.11 0.02 0.00 0.04 0000 --- --- --- --- 022985 00000 ------------ T 0.90 1.00 1.00 0.97 C 0.10 0.00 0.00 0.03 0000 --- --- --- --- 022997 00000 ------------ C 1.00 1.00 0.98 0.99 T 0.00 0.00 0.02 0.01 0000 --- --- --- --- 023037 00000 ------------ T 0.93 0.96 0.96 0.95 G 0.07 0.04 0.04 0.05 0000 --- --- --- --- 023508 00000 ------------ A 0.38 0.69 0.67 0.59 G 0.62 0.31 0.33 0.41 0000 --- --- --- --- 023696 01696 3' UTR G 0.91 0.88 0.85 0.88 A 0.09 0.12 0.15 0.12 0000 --- --- --- --- 023796 00000 ------------ G 0.57 0.81 0.83 0.74 C 0.43 0.19 0.17 0.26 0000 --- --- --- --- 023830* 024499 00000 ------------ C 0.93 1.00 1.00 0.98 T 0.07 0.00 0.00 0.02 0000 --- --- --- --- 024586 00000 ------------ G 0.93 1.00 1.00 0.98 T 0.07 0.00 0.00 0.02 0000 --- --- --- --- 024881 00000 ------------ 0000 025064 00000 ------------ T 0.84 1.00 1.00 0.95 C 0.16 0.00 0.00 0.05 0000 --- --- --- --- 025218 00000 ------------ A 0.98 1.00 1.00 0.99 G 0.02 0.00 0.00 0.01 0000 --- --- --- --- 025425 00000 ------------ T 1.00 0.83 0.77 0.86 C 0.00 0.17 0.23 0.14 0000 --- --- --- --- NOTE: AD-freq: African Descent frequency ND-freq: North Karelia frequency RD-freq: Rochester, MN frequency NOTE: Diallelic insertion/deletion polymorphisms are represented as: + : allele insertion - : allele deletion The + (inserted) allele for each site is listed below: 003379: A 005810: G 007283: CACA 015689: A The following site(s) was observed to have three alleles. The frequency for each allele is given below: Site Allele1 AD-freq AD-freq AD-freq Total-freq Allele2 AD-freq AD-freq AD-freq Total-freq Allele3 AD-freq AD-freq AD-freq Total-freq 023830 A 0.35 0.69 0.69 0.58 C 0.02 0.00 0.00 0.01 G 0.63 0.31 0.31 0.42